Gene Ontology consistent protein function prediction: the FALCON algorithm applied to six eukaryotic genomes
نویسندگان
چکیده
منابع مشابه
Predicting Protein Function with Hierarchical Phylogenetic Profiles: The Gene3D Phylo-Tuner Method Applied to Eukaryotic Genomes
"Phylogenetic profiling" is based on the hypothesis that during evolution functionally or physically interacting genes are likely to be inherited or eliminated in a codependent manner. Creating presence-absence profiles of orthologous genes is now a common and powerful way of identifying functionally associated genes. In this approach, correctly determining orthology, as a means of identifying ...
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Protein function prediction, in the context of the Gene Ontology, is a task that consists of answering, for a fixed protein X, a large number of binary questions of the form: " Does protein X belong to GO term Y ? " Those binary classification problems are strongly related because the ontology consists of nested classes. Two natural requirements for this prediction problem are • that the set of...
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ژورنال
عنوان ژورنال: Algorithms for Molecular Biology
سال: 2013
ISSN: 1748-7188
DOI: 10.1186/1748-7188-8-10